Monday, December 30, 2019

Beowulf The Epic Poem From The Anglo Saxon Period

Beowulf, the longest epic poem from the Anglo-Saxon period, has a protagonist named Beowulf. A hero of the Geats and forthcoming king, the title character comes to the aid of Hrothgar, king of the Danes, whose kingdom was under attack by a monster known as Grendel. Both are great kings, wise and noble, but what truly makes a king great? Is it the accolades or honors that one receives or does it go beyond that? Two different cultures, two different men, but two great kings; Beowulf was described as a hope for the people (l. 13, 36). He was a hope for the Geats in his ability to lead, to fight and to inflict change. Even Hrothgar voiced to Beowulf that he have heard no man of the age that you are utter such wisdom. You are rich in strength and ripe of mind, you are wise in your utterance (ll. 1840-43, 77). After defeating Grendel and his mother, Hrothgar tells Beowulf this. This foreshadows that Beowulf will be a mighty king in the future. Both are men whom people counted on and looked to for guidance. Both exemplifying what a ferocious warrior resembled and what a true hero was. Hrothgar was granted glory in battle, mastery of the field (ll. 63-4, 38). Knowing from experience, the glory of being looked up to as a hero, Hrothgar warns Beowulf of pride and arrogance. He tells Beowulf a story about Heremod, a fighter once known for being brave and destroyed all obstacles that came his way, but turned into a monster himself when he became blood-thirsty. Beloved Beowulf,Show MoreRelatedEpic Poetry and Beowulf Pg1086 Words   |  5 PagesEpic poems have a unique set of characteristics that distinguish them from just an ordinary poem. An epic poem must contain a hero that is male, noble, and of importance to society who gives long formal speeches and travels over a vast setting. In the epic poem, Beowulf, the reader can see distinct Anglo-Saxon political, economic, and religious values in the actions of the characters and the things happening around them. Wealth in the Anglo-Saxon society, as seen in Beowulf, was used as a means ofRead MoreAngloSaxon Literature Essay632 Words   |  3 Pagesthroughout the Anglo-Saxon Period (449-1066), we see that many of their narratives, stories were simply passed down orally due to the lack of education prior to the era of Christianity. During the Anglo- Saxon Era literature initially began to be written down by the monks of the Christ ian Monasteries. The Anglo-Saxons contributed many details to human nature. The Anglo-Saxons named our modern day weekdays after Greek Gods. Heroism within an epic poem was often present during this period. Epic poetryRead MoreBeowulf : The Ideal Anglo Saxon Warrior871 Words   |  4 PagesMaya Rhode The Ideal Anglo-Saxon Warrior Throughout the epic of Beowulf, the differences between the hero of Beowulf and the villain of Grendel are made clear. Taking place during the fifth century, Beowulf is commonly known as the oldest surviving epic poem of Old English. It is also considered one of the most important works of Anglo-Saxon literature. With a different age and time period comes different values. Many of the traits greatly admired during the time of Beowulf may now have much lessRead MoreThe Anglo Saxon Era Of Rich History And Reflected Literature1486 Words   |  6 PagesThe Anglo Saxon Era of Rich History and Reflected Literature The Anglo Saxon Period began in 449 and ended in 1066 AD. This was a time of Viking conquering other nations, patriotism, and Pagan to Christian religious conversion. There are only few recorded authors of this era as a result of literary works such as Beowulf, Wife’s Lament, and The Seafarer being passed down orally through generations of time. The literature serves as a reflection of this ancient time rather than having an impact on thisRead MoreBeowulf: An Analysis1615 Words   |  7 Pages11/26/10 Beowulf Anglo Saxons are Germanic people that lived during the 5th and 6th centuries. This early Anglo-Saxon society was centered on families and clans. The earliest Saxon settlers and families in England were pagans who worshipped a number of gods. Although Anglo Saxons had unalterable beliefs, Christians eventually purveyed their religion upon the pagans. However, the ideals of paganism still perpetuate through the most prominent epic poem of this era called Beowulf. Beowulf embodiesRead MoreBeowulf And The Anglo Saxon Period1740 Words   |  7 PagesBeowulf The original poem, Beowulf, goes back to the Anglo-Saxon period in c. 650 and c.1100. Authors translated Beowulf many times in the Anglo-Saxon period to present day. It displays how a hero should be in the real world. He helps the people in the village and slays monsters. Everyone in the village looks up to him as he acts as if he were a role model. Beowulf, the protagonist in the translated Beowulf by Seamus Heaney, is a hero of his village, stands for bravery, strong will, and noblenessRead MoreEssay about Epic of Beowulf1017 Words   |  5 PagesBeowulf The Anglo-Saxon Culture as Illustrated in Beowulf Beowulf is an epic poem, which takes place in ancient Denmark and Geatland and describes the adventures of Beowulf, a Geat hero. Through their heroes, epic poems usually describe the traditions and beliefs of a certain culture. An Anglo-Saxon author wrote Beowulf about the Danes and Geats. The Anglo-Saxon’s had similar beliefs to that of the Dane and Geat’s, so the poem gives us some idea of what the Anglo-Saxon culture was like.Read MoreCompare and Contrast of Beowulf and Sir Gawain and the Green Knight600 Words   |  3 Pagesand Contrast of Beowulf and Sir Gawain and the Green Knight Beowulf is an epic poem that was written in the Anglo-Saxon time period where only a few privileged people were able to read and write while Sir Gawain and the Green Knight, which is also an epic poem, was written in the Middle English time period where reading and writing was more wide-spread. While both the epic poem Beowulf and Sir Gawain and the Green Knight have similar protagonists, the main character of each poem also has differentRead More Beowulf and The Intent of Christians to Convert Pagans Into Christianity 1069 Words   |  5 Pagesthen the Anglo Saxons. The Anglo Saxon’s traveled to England from the northern countries of Germany Norway and Sweden. When they arrived, they brought their gods with them. The Anglo Saxon’s religion consisted of multiple gods and goddesses and their own view of Heaven and what it would be like. The Anglo Saxon’s also loved poetry, and they used it to keep track of the history of their people. Beowulf is an epic poem tha t was past down by the Anglo Saxons from generation to generation. The poem is infusedRead MoreWilliam Shakespeare s Beowulf And The Genesis Of The Beowulf1321 Words   |  6 Pages During the Anglo-Saxon period, it was considered a dishonor if one failed to avenge the death of a family member. Wergild is a sign of loyalty, which is a recurring theme throughout in Beowulf. In the epic, not only did Beowulf seeks wergild for the death of his friend, but Grendel’s mother looks to avenge her son’s death. The need for wergild is a constant theme in the epic. In order to understand the poem Beowulf and the importance of wergild, one must understand the time period it was written

Sunday, December 22, 2019

Essay about Should Illegal Immigrants Be Granted Amnesty

According to CNN, 12 million illegal immigrants currently reside in the United States, which is approximately equivalent to the populations of Illinois, Pennsylvania, Ohio, or Michigan. Removing all 12 million illegal immigrants, then, would be like removing one of the above states, a pretty incredulous task. In practical terms, it is not possible to send that many immigrants back to their respective countries efficiently and economically. This raises the issue of what to do with the immigrants that are already here, and how to increase security to keep the number of illegal immigrants entering under control. It may be feasible to grant citizenship to those illegal immigrants that have been in the United States for some time, however;†¦show more content†¦This is amnesty, and I oppose it†¦ Amnesty would be unfair to those who were here lawfully, and it would invite further waves of illegal immigration†¦Ã¢â‚¬  Additionally, Robert Byrd (Senate) stated in his exce rpts from his Address to the United States Senate, â€Å"To capriciously grant amnesty to three million immigrants who circumvented these processes, who have resided and worked in this country illegally, sends exactly the wrong message†. The wrong message being that amnesty only invites more illegal immigrants into the country without reprimanding the ones who are currently here. However, the secondary problem here, as Bush recognized and stated is that, â€Å"†¦it is neither wise, nor realistic to round up millions of people, many with deep roots in the United States, and send them across the border†. Admittedly, amnesty seems to manifest several problems, mainly with continued unlawful immigration, however; it does not make sense to send millions of integrated immigrants out of the country. Instead, a partial amnesty could be granted, which would be fairer to lawful immigrants, but also give illegal immigrants a chance to lawfully obtain citizenship and contin ue living in the United States. To become a citizen, the immigrants have to apply for application costing 680 for the application for citizenship, 595 for the application, and 85 for the finger printing fee. Furthermore be aShow MoreRelatedArgumentative Essay on Immigration1148 Words   |  5 PagesIllegal Immigration Amnesty There are many problems that the United States faces and the one that is causing several debates is illegal immigration. Thousands and thousands of illegal immigrants have come from many different places. All of them have different desires. One might want a safe future for their family, one is probably looking for a fresh start, or even a place to spread their knowledge. The big question is should illegal immigrants be granted amnesty? After the resourcesRead MoreFamily Values Linda Chavez Summary1304 Words   |  6 PagesAre Immigrants actually hurting America? In the article â€Å"Supporting Family Values† Linda Chavez writes to inform Americans about immigrants. In American people make the assumption that immigrants are here to hurt America instead of improving America. In reality there is only a small group of immigrants that hurt America. People need to separate the groups to realize that there are immigrants who help America and that they should be allowed to stay in America under certain circumstances. ImmigrantsRead MoreImmigration And The United States Essay1368 Words   |  6 Pagesmust be addressed: what to do with illegal immigrants already in the United States, how to stop future illegal immigration, and how to improve and streamline the process of legal immigration. Illegal Immigrants Currently in the United States Illegal immigrants currently in the United States need a path towards citizenship unless they are violent criminals. There are currently approximately 11 million illegal immigrants in the United States. While these immigrants have broken the law, deporting allRead MoreUndocumented Immigrants Should Be Legal949 Words   |  4 Pagesnation of immigration but America also faces the problem of illegal immigration. In America the debate of whether undocumented immigrants should be able to get full amnesty is still a controversy. Even though illegal immigrants did make an illicit action, many see the United States as an opportunity for a better future. In addition, undocumented immigrants should be granted citizenship because it will benefit the United States. Creating an amnesty for the students will help the United States by improvingRead MoreThe Immigration Of The United States1711 Words   |  7 Pagesvast majority of people living in the United States are descendants of immigrants , and yet majority of them are against them. It is quickly forgotten that America was built on immigrants that wanted a new life. A life free from harsh government, and the freedom from forced religion. The original settlers were immigrants that stole this land; immigrants continued to come for years. It is not a newly constructed concept that immigrants have always been a problem, ask any Native American. One used to beRead MoreIllegal Immigration And Illegal Immigrants1793 Words   |  8 Pagesrecent discussion s of illegal immigration, a controversial issue has been whether or not to grant amnesty to illegal immigrants in the U.S. On the one hand, some argue that amnesty shouldn’t be granted to illegal criminals. From this perspective, there are downfalls that many ignore and is unjust and stereotypical that all illegals are dangerous criminals. On the other hand, however, others argue that amnesty should be granted to illegal immigrants and how all of us are immigrants. In the words of oneRead MoreIllegal Immigration And The United States1624 Words   |  7 PagesWhy is illegal immigration often viewed as a threat to the United States rather than being unscrupulous? With over 11.5 million illegal immigrants in the Unites States, opponents of illegal immigration dispute that concept of granting amnesty to these immigrants. These arguments include that certain jobs will be stolen, and an increase in crime rate would develop. Despite the fact that illegal immigration is controversial, recent studies and social trends have shown that granting amnesty to illegalRead MoreIllegals Are Costing Americans A Lot Of Money1289 Words   |  6 Pagesundocumented illegals in our country today. Only about .5% is sent back to their home country. That is too many illegals for the U.S. to take care of, and a lot of them are taking American jobs increasing our unemployment rate. Most of these Illegals bring in many drugs so they can get money to start a new life. Th ere are too many Illegals coming into our county its’s a problem and we need to change that. Illegals are costing Americans a lot of money. In 2000 Mexico proposed that its poor works should beRead MoreAmnesty for Illegal Immigrants795 Words   |  4 PagesShould the United States Grant amnesty to immigrants who came here illegally? By: Chris Myers Should the U.S. grant amnesty to immigrants who came here illegally? The answer to this question is yes, they should. What s wrong with granting amnesty to hard-working, tax-paying individuals whose only crime is their immigration status? Amnesty is not only the best solution to our immigration problem, it is the only feasible solution. Here are some reasons to grant amnesty to illegal immigrantsRead MoreIllegal Immigration1570 Words   |  7 Pages English 102 25 June 2013 Illegal Immigration Illegal Immigration has been a problem for a very long time now in the United States. It has also been a very controversial subject for as long as I can remember. Illegal immigration goes back hundreds and thousands of years. Living in such an anti-illegal immigration state has been tough, there is always something about illegal immigration laws going on, and politics talking about it and the saddest part families being separated, daily.

Saturday, December 14, 2019

Advanced Paramedical Science Free Essays

string(58) " and vomiting are commonly encountered clinical problems\." Nausea and vomiting is a commonly encountered problem in the emergency department as it accompanies a multitude of conditions ranging from seemingly benign conditions such as migraine and gastroenteritis to potentially lethal conditions such pancreatitis and the acute abdomen. Studies from the U.S have shown that each year, almost 8 million individuals present to the emergency department with complain of nausea and vomiting, either as a principal complain or as a part of another disease etiology (Braude, Soliz, Crandall, Hendey, Andrews, Weichenthal, 2006, p. We will write a custom essay sample on Advanced Paramedical Science or any similar topic only for you Order Now 77). Nausea and vomiting are not distinct disease entities. Rather, they are symptoms which can be present in a wide range of disease conditions and are considered to be the ‘end-points’ of several pathological processes (Klosterhalfen and Enck cited in Kowalski, Rapps, Enck, 2006 p.28). The term nausea refers to the subjective feeling or the urge to regurgitate gastric contents (Kuver, Sheffield, McDonald, n.d.). From a physiological point of view, this is associated with reduced gastric motility and increased smooth muscle tone of the small intestine. Moreover, there might also be the presence of reverse peristalsis in the small intestine, which can cause the feeling of imminent regurgitation (Bowen, n.d.). On the other hand, vomiting refers to ‘the forceful discharge of gastric contents’ (Kuver, Sheffield, McDonald, n.d.) which is meant to serve the purpose of protecting the gastrointestinal tract from potentially harmful substances by preventing their entry and transit through the gastrointestinal tract (Kuver, Sheffield, McDonald, n.d.). Vomiting, if persistent can have several potentially hazardous consequences such as dehydration, electrolyte imbalances, metabolic derangements, manifesting as alkalosis and even bleeding and esophageal perforation (Kuver, Sheffield, McDonald, n.d.). Moreover, from the patient’s perspective, nausea and vomiting can be distressful and thus appropriate and timely management of these two conditions is imperative. The Physiology of Nausea and Vomiting – an overview of the stimuli and pathway involved For several decades now, it has been established that the chemoreceptor trigger zone in the brain which is responsible for emesis is the area posterema. This is a region located at the dorsal surface of the medulla oblongata near the caudal end of the fourth ventricle. It is one of the ‘circumventricular organs’ and by the virtue of possessing a relatively permeable blood-brain barrier, is sensitive to a variety of stimuli (Sanger Andrews, 2006, p. 5). Thus, it plays an important role in emesis. Studies have shown that there are five main kinds of stimuli which can trigger nausea and vomiting via different pathways viz. the presence of toxic materials within the gut lumen, presence of toxins in the blood, a pathology within the gut, a central nervous system (CNS) stimulus or disturbances in the vestibular system (Sanger Andrews, 2006, p. 5). The mechanism whereby each of these stimuli brings about nausea and vomiting is discussed below. The presence of toxic materials within the gut lumen: The presence of toxins, such as drugs has been shown to stimulate the enteroendocrine cells, such as the enterochromaffin cells, located in the gut mucosa and result in the release of several mediators such as 5HT3, Substance P and CCK. This results in the stimulation of vagal afferent neurons which are located in the abdomen. These neurons traverse through the nucleus tractus solitarius (NTS) and are projected to the dorsal brainstem, with some projection in to the area posterema (Sanger Andrews, 2006, p. 5). Presence of toxins in the blood Toxins which have been absorbed and are circulating in the bloodstream can directly stimulate the area posterema and cause induction of emesis (Sanger Andrews, 2006, p. 5). This is the most common mechanism whereby ingested or parenterally administered drugs, such as chemotherapeutic agents and other toxins such as drugs of abuse, invoke the emetic response. Gastrointestinal tract pathologies Certain pathologies of the gastrointestinal tract, such as gastritis or hypertrophic pyloric stenosis can stimulate the vagal afferents or directly activate the pathways leading to emesis (Sanger Andrews, 2006, p. 6). Central nervous system (CNS) stimuli Certain stimuli such as intense fear, anticipatory anxiety, injury to the brain or a sudden increase in the intracranial pressure can induce emesis (Sanger Andrews, 2006, p. 6). The mechanism involved in such a response has not yet been elucidated clearly. Disturbances in the vestibular system Amongst other manifestations of disturbances in the vestibular system, such as dizziness, nausea and vomiting is also an important symptom. The vestibular system has been shown to directly stimulate the pathways involved in the emetic response and hence produce nausea and vomiting (Sanger Andrews, 2006, p. 6). All these stimuli have been shown to stimulate various pathways which have one common outcome viz. the stimulation of the emetic center in the area posterema. (Kuver, Sheffield, McDonald, n.d.). Several receptors, both central and peripheral, have been implicated in bringing about emesis. Amongst these the most pertinent ones are Dopaminergic receptors (particularly D2), Histaminergic receptors (especially H1), Muscuranic receptors (including M3/M5), 5-hydroxytryptamine receptors, in particular, 5-HT3 and the neurokinnin receptor, NK1 (Sanger Andrews, 2006, p. 8) Once any of the above mentioned stimuli are encountered, an afferent response as discussed above is generated. This results in the activation of the chemoreceptor trigger zone in the area posterema. Subsequently, a motor response is generated, whereby efferent pathways involving the cranial nerves V, VII, IX and X are activated. Moreover, autonomic responses are also generated (Kuver, Sheffield, McDonald, n.d.). The vagal efferents to various muscle groups such as those located in the esophagus, stomach and the intestine are activated bringing about stimulation of these muscles (Sanger Andrews, 2006, p. 6). Moreover, abdominal muscles, phrenic muscles and the diaphragm are also stimulated to bring about the required increase in the intra-abdominal pressure. The combination of both these effects leads to the regurgitation of the gastric contents. Moreover, this is also accompanied by various other manifestations such as an increase in salivation, brought about by the stimulation of the chorda tympani branch of the facial nerve, autonomic stimulation of the cardiovascular and respiratory systems and vasoconstriction of skin vessels (Sanger Andrews, 2006, p. 6). Antiemetic drugs used in pre-hospital care Nausea and vomiting are commonly encountered clinical problems. You read "Advanced Paramedical Science" in category "Papers" Over the years, several anti-emetic medications have been discovered to effectively alleviate the symptoms of nausea and vomiting. These drugs work by blocking the pathways involved in the initiation and production of emesis. Various drugs have been developed which block the different receptors, both central and peripheral, involved in producing emesis. The anti-emetic medications which are used in common clinical practice can be grouped in to seven major categories according to their mode of action. These include anti-cholinergics, antiserotonins, antihistamines, Benzamides, Butyrophenones, Phenothiazines and steroids (Scuderi, 2003, p. 43). The mechanism of action and the dosages of the four main anti-emetics used in Ambulance Services in Australia are discussed below: 1.  Ã‚  Ã‚  Ã‚  Ã‚   Metoclopramide (Maxolon): Metoclopramide has been used in clinical practice for several decades now as an antiemetic and a prokinetic agent (Walkembach, Bruss, Urban, Barann, 2005, p. 50). These antiemetic functions are thought to be brought about by the antagonistic actions of Metoclopramide on the dopamine (D2) receptors, both central and peripheral, and also on the 5HT3 receptors (Walkembach, Bruss, Urban, Barann, 2005, p. 50). On the other hand, the prokinetic action of Metoclopramide are brought about by the relaxation of the pyloric sphincter, the increase in the strength and frequency of peristalsis and an increase in the tone of the lower esophageal sphincter (Australasia, 2008). This drug is available in both tablet (white, round, 7mm in diameter) and injection (colorless, aqueous solution) forms (Australasia, 2008). The maximum dose of Metoclopramide commonly used in all age groups is up to 0.5 mg/kg body weight. The recommended dosage regimen for adults is 10mg three times daily while for children it varies between 2.5mg-5mg   three times daily (Australasia, 2008). The metabolism of Metoclopramide takes place in the liver and it is eliminated from the body predominantly via the kidney. (Australasia, 2008) 2.  Ã‚  Ã‚  Ã‚  Ã‚   Prochlorperazine (Stemetil) Prochlorperazine is a phenothiazine which has been shown to block the dopamine receptors (D2) in the chemoreceptor trigger zone located near the area posterema. By blockage of these receptors, Prochlorperazine exerts its antiemetic actions. The recommended dosage of Prochlorperazine in is 10 mg intravenously (Goodman and Gilman’s: The Pharmacologic Basis of Therapeutic cited in Ernst, Weiss, Park, Takakuwa, Diercks, 2000, p. 92). In emergency practice, IV administration of 2.5-10 mg of Prochlorperazine at a rate of up to 5mg/min is recommended for adults. The maximum dose should not exceed 40mg per day. Moreover, IM injections of this drug are also available. They are administered at a dose of 5-10 mg every 3-4 hours (Bartlett, 2009, p. 861). 3.  Ã‚  Ã‚  Ã‚  Ã‚   Ondansetron (Zofran) Ondansetron is a carbazole derivative and is a potent antiemetic drug which is widely used in alleviating the symptoms of nausea and vomiting associated with chemo- and radio- therapies and also in the management of post-operative nausea and vomiting (Scuderi, 2003, p. 59). Its proposed mechanism of action is via selective antagonism at the level of the 5 HT3 receptors (Scuderi, 2003, p. 59). Chemotherapeutic agents are thought to bring about nausea and vomiting via the stimulation of enterochromaffin cells in the gut mucosa leading to 5HT3 production and subsequent vagal stimulation. This pathway is blocked by 5HT3 antagonists such as Ondansetron. Ondansetron has been shown to have a short half life of approximately 3 to 5 h (Ho Gan, 2006, p. 607). The recommended dosage of Ondansetron varies between 8-16 mg twice daily (Bartlett, 2009). 4. Promethazine (Phenergan) Promethazine is also a phenothiazine but is shown to have dual modes of action. It not only blocks the dopamine receptors (D2) but has also been shown to have anti-H1 histamine receptor effects. It is used for a wide range of purposes including in the treatment of motion sickness, vertigo and even allergies (Bartlett, 2009, p. 869). The recommended oral dose of Promethazine is 25 mg twice daily. It can also be administered intravenously at a dose of 12.5-25 mg every four hours. The maximum dose is 150 mg/day (Bartlett, 2009, p. 869). PART II There are several clinical conditions which can present with the symptoms of nausea and vomiting. Amongst these the most common condition is gastroenteritis, migraines and pancreatic amongst others. The adequate and timely management of patients with nausea and vomiting has posed a challenge for the clinicians for several decades and although several effective anti-emetics have been discovered, there has been a quest for a single anti-emetic which is efficient, fast acting and relatively safe. In the practice of ambulance services and emergency situations, different anti-emetics are commonly used including Metoclopramide, Chlorpromazine, Ondansetron and Promethazine. Amongst these, in my opinion, the most suitable drug for use in the ambulance service and emergency departments is Metoclopramide. This is because on comparing the onset of action, clinical efficacy and side effect profiles of the most common anti-emetic agents, it is apparent that Prochlorperazine is superior to all other agents used. Moreover, its cost, availability and easy administration make it suitable for use in the emergency practice. Following is a comparison of the four most commonly used anti-emetic drugs. A common concern with the use of any drug is its safety and side effect profile. Safety becomes more important while dealing with patients in the emergency or ambulance care since limited resources, time and personnel are available in such settings, and the prime concern is the stabilization of the patient and alleviation of his symptoms. Drugs which have potentially unsafe need to be administered with caution and the patients need to be monitored for the occurrence of adverse effects. This is not feasible in emergency and ambulance practice and thus the ideal drugs for use in such settings are those which have no or minimal side effects. With Metoclopramide, there is a 10-20% incidence of side effects and these side effects are mild. The most common side effects observed with this drug are CNS effects such as anxiety, restlessness and insomnia which can vary in severity (Australasia, 2008). Moreover, it has also been shown to cause fatigue and occasionally can cause extrapyramidal side effects. Another relatively common side effect of Metoclopramide is gynecomastia which occurs as a result of enhanced prolactin secretion (Kuver, Sheffield, McDonald, n.d.). A rare complication associated with the use of Metoclopramide is Neuroleptic Malignant Syndrome which is a medical emergency and can lead to death. However, it is observed in only less than 1 in 10,000 cases (Australasia, 2008) . On the other hand, the phenothiazines including Prochlorperazine and Promethazine have been shown to have a greater number of side effects. Amongst these the ones which arouse the most concern are extrapyramidal symptoms. Extrapyramidal symptoms can range from tremor to akathisia and the potentially hazardous tardive dyskinesias (Australia, 2009). Moreover, they can also manifest as dystonic reactions are similar to the manifestations of Parkinson’s disease. Less commonly, Neuroleptic Malignant Syndrome, which is a medical emergency, can also result from the use of these drugs. These effects are thought to be caused due to the central antidopaminergic properties of the phenothiazines on the dopamine receptors. The occurrence of these symptoms is noticed most commonly within 36 hours of initiation of treatment. However, these symptoms are reversible and once the drug is discontinued, they disappear within 24 hrs (Australasia, 2008). It is important to note that with Metoclopramide, the occurrence of extrapyramidal side effects is not very common. On the other hand, the phenothiozones such as Prochlorperazine and Promethazine have a much greater incidence of these side effects. Drotts and Vinson (1999) in their study showed that with the use of Prochlorperazine, incidence of akathisia was 44% within 1 hour and 5% within 48 hours. (Braude, Soliz, Crandall, Hendey, Andrews, Weichenthal, 2006, p. 181). Other studies, such as those of Ernst et. al., have supported these findings. These extrapyramidal symptoms, if severe, have to be treated with intravenous infusions of an anti-cholinergic agent such as diphenhydramine (Ernst, Weiss, Park, Takakuwa, Diercks, 2000, p. 92). Other common side effects of phenothiazines include constipation, blurred vision, mild elevation of the hepatic enzymes (if the patient develops cholestatic jaundice), ECG changes, arrhythmias and hypotension (Australia, 2009). Hypotension in patients who are already dehydrated due to vomiting can lead to significant patient distress and is also important from the point of view of health care professionals, as it poses difficulties in patient management in emergency and ambulance settings. Moreover, most phenothiazines, in particular Promethazine are known to cause sedation due to histamine blockade. Promethazine has also been shown to reduce the seizure threshold. Due to the multitude of serious adverse effects of Promethazine the Food and Drug Administration (FDA) has restricted its use in children under two years of age (DeCamp, Byerley, Doshi, Steiner, 2008, p. 859). As compared to Metoclopramide, Ondansetron has relatively lesser side effects. The most commonly encountered adverse effects of this agent include headaches, constipation and mild elevation of serum transaminases (Kuver, Sheffield, McDonald, n.d.). But this drug is not preferred over other anti-emetic agents due to its cost and availability issues (Ernst, Weiss, Park, Takakuwa, Diercks, 2000, p. 92). Moreover, it is used more commonly to prevent post-operative nausea and vomiting and in patients receiving chemotherapy and its role in acute settings has not been extensively studied. Pregnancy is one of the most common conditions which present with nausea and vomiting.   Amongst the commonly available anti-emetics only a few are safe to use in pregnancy. Studies have shown Metoclopramide to be safe for use during pregnancy and this drug has not been shown to cause any long term complications in children of mothers using it during pregnancy (Sà ¸rensen, Nielsen, Christensen, Tage-jensen, Ekbom, Baron, 2000). Similarly the safety of Ondansetron has also been proven by several studies conducted recently (Einarson, Maltepe, Navioz, Kennedy, Kennedy, Koren, 2004, p. 940). However, both Promethazine and Prochlorperazine belong to Category C and thus   have limited use in pregnancy (Australia, 2009). Another advantage of Metoclopramide is its ability to provide faster relief from the symptoms of nausea and vomiting. Metoclopramide has been shown to have a rapid onset of action. Following IV administration, its effects start manifesting in around 1 to 3 minutes, whereas following intramuscular administration, 10 to 15 minutes is required (Australasia, 2008). This rapid action makes it suitable for use in emergency practice, Although there is a paucity of studies comparing the cost effectiveness of Metoclopramide with other antiemetics, studies comparing the cost-effectives in patients undergoing chemotherapy have shown that Metoclopramide to be more cost effective than Ondansetron (Ballatori, et al., 1994). Thus, in conclusion, keeping the side effect profiles, the availability and cost effectiveness of all the anti-emetics in view, in my point of view Metoclopramide is best suited for use in ambulatory settings. Metoclopramide has several benefits over other anti-emetics. It has a fast onset of action which makes its practical for use in emergency settings. Moreover, it has lesser and milder adverse effects as compared to other anti-emetics. In addition, it can be used in all age groups and is safe in pregnancy. Thus, all these properties make Metoclopramide ideal for use in ambulatory care settings. References Australasia, V. P. (2008, October 22). Metoclopramide hydrochloride-Data sheet. Retrieved May 1, 2009, from Medsafe-INFORMATION FOR HEALTH PROFESSIONALS: http://www.medsafe.govt.nz/Profs/datasheet/m/Maxolontabsyrinjsupp.htm Australia, S.-A. (2009). Sanofi-Aventis Australia. Retrieved May 1, 2009, from Product Information: http://www.sanofi-aventis.com.au/products/aus_pi_phenergan.pdf Ballatori, E., Roila, F., Berto, P., De Angelis, V., Neri, C., Olivieri, A., et al. (1994). Cost and cost-effectiveness analysis of ondansetron versus metoclopramide regimens: a hospital perspective from Italy. Pharmacoeconomics , 227-37. Bartlett, J. . (2009). 2009 Nurse’s Drug Handbook . Jones Bartlett . Bowen, R. (n.d.). Physiology of Vomiting. Retrieved May 1, 2009, from The Stomach: http://www.vivo.colostate.edu/hbooks/pathphys/digestion/stomach/vomiting.html Braude, D., Soliz, T., Crandall, C., Hendey, G., Andrews, J., Weichenthal, L. (2006). Antiemetics in the ED: a randomized controlled trial comparing 3 common agents. American Journal of Emergency Medicine , 177–182. DeCamp, L. R., Byerley, J. S., Doshi, N., Steiner, M. J. (2008). Use of Antiemetic Agents in Acute Gastroenteritis:A Systematic Review and Meta-analysis. Archives of pediatric and adolescnet medicine , 858-865. Drotts, D. L., Vinson, D. R. (1999). Prochlorperazine Induces Akathisia in Emergency Patients. Annals of Emergency Medicine . Einarson, A., Maltepe, C., Navioz, Y., Kennedy, D., Kennedy, D., Koren, G. (2004). The safety of ondansetron for nausea and vomiting of pregnancy:a prospective comparative study. BJOG: an International Journal of Obstetrics and Gynaecology , 940–943. Ernst, A. A., Weiss, S. J., Park, S., Takakuwa, K. M., Diercks, D. B. (2000). Prochlorperazine Versus Promethazine for Uncomplicated Nausea and Vomiting in the Emergency Department: A Randomized,Double-Blind Clinical Trial. Annals ofEmergency Medicine , 89-94. Ho, K.-Y., Gan, T. J. (2006). Pharmacology, pharmacogenetics, and clinical efficacy of 5-hydroxytryptamine type 3 receptor antagonists for postoperative nausea and vomiting. Current Opinion in Anaesthesiology , 606–611. How to cite Advanced Paramedical Science, Papers

Thursday, December 5, 2019

Tiger Subspecies Essay Research Paper Tiger SubspeciesI free essay sample

Tiger Subspecies Essay, Research Paper Tiger SubspeciesI am here composing a study on the sub species of Liberation Tigers of Tamil Eelams. Many of these Liberation Tigers of Tamil Eelams will non last in the following 40 old ages due to the violent death that us worlds have caused. Tiger sub species have non been every bit of import to us worlds as whether or non the species Tiger Panthera Tigris can last either in the natural state or in imprisonment for the following 40 old ages. However a great trade of information on the hereafter of the tiger can be learned from a survey of races. Which is what my study will be based on. It is astonishing to me that people want Numberss of Liberation Tigers of Tamil Eelams. Procedure is the of import facet. If I say that the figure of Sumatra Liberation Tigers of Tamil Eelams today is between 300 and 400, it doesn # 8217 ; t state one that the 1975 nose count was 1500. We will write a custom essay sample on Tiger Subspecies Essay Research Paper Tiger SubspeciesI or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page Therefore stating that the Bali tiger, theCaspian tiger, the Javan tiger, the Manchurian tiger, and the Southwest Chinese tiger are now nonextant doesn # 8217 ; t give you aportrait of the procedure of extinction. The Javan tiger became nonextant in the 1970 # 8217 ; s in a set aside particular national park under full protection. Politicans and administrative officials seem to be obsessed with Numberss and non tendencies. Let me exemplify this with Liberation Tigers of Tamil Eelams. There are often petitions as to the exact figure of Liberation Tigers of Tamil Eelams, or a tiger subspecies left in the universe. That tells you that there are people that attention. But there are so small Liberation Tigers of Tamil Eelams left that we can non even maintain path of them. We should look at the tendency that the population is taking, instead than the figure as a piece in clip. Merely as you might state of a immature member of the Hunt household, that they were really affluent. A conjec tural person was 24 old ages o ld and had $ 1,000,000. What isn’tavailable in this one clip analysis was that this Hunt inherited $ 24,000,000 at age 21, has no instruction nor of all time worked. At age 22 Hunt had $ 9,000,000 and at 23 had $ 4,000,000. Now alternatively of stating Hunt was rich, we would state Hunt is in problem. Lttes are a great trade like Hunt. The estimations of Liberation Tigers of Tamil Eelams are from the Carnivore Preservation Trust has arrived at their ain estimations ; they are extremely educated conjectures: Bengal Liberation Tigers of Tamil Eelams likely figure fewer than 1000 in India. In bulk of that state it is hopelessly fragmented. It is, overall, actively poached. Fewer than 200 exist in Nepal and under 1000 exist in Myammar ( Burma ) . Indochinese Liberation Tigers of Tamil Eelams are among 500 and 2000. CPT # 8217 ; s conjecture is about 700 amidst heavy poaching. In the early 1960ss when the South China tiger had apopulation of about 4,000, Mao instituted a tiger obliteration plan. After Mao # 8217 ; s decease in 1976, the South China tigerpopulation was reduced to 400. The Chinese authorities so instituted a # 8220 ; Save the Tiger Program! # 8221 ; South Chinese tiger isabout 25, but the wild figure is so inbred that the effectual population figure is more like four! The Siberian tiger numberis between 125 and 175. ( Closer to 125 harmonizing to the Russian scientist whowas enrolling for the geneticmanagement of the free ranging Siberian tiger plan in October 1995. ) We must make something to halt the extincian of one of our must beautiful animate beings. We have lost to many species of animate beings and we can non afford to lose any more. As we can see, at the rate that we are losing animate beings in the universe, reasonably shortly there are non traveling to be any left for us to bask.